| تعداد نشریات | 38 |
| تعداد شمارهها | 1,408 |
| تعداد مقالات | 10,088 |
| تعداد مشاهده مقاله | 11,909,071 |
| تعداد دریافت فایل اصل مقاله | 6,961,217 |
تحلیل روند تحقیقات جهانی درباره نانوذرات هوا و ناباروری در دو دهه اخیر: رویکرد علمسنجی و نقشهبرداری موضوعی | ||
| فصلنامه حکمرانی جمعیت و خانواده | ||
| مقاله 6، دوره 2، شماره 3 - شماره پیاپی 5، مهر 1403، صفحه 117-139 اصل مقاله (1.93 M) | ||
| نوع مقاله: مقاله مروری | ||
| نویسندگان | ||
| محمد عارفخانی* 1؛ زهرا قربانی2؛ امیر رضائی3 | ||
| 1دانشجوی دکتری، گروه سلامت جمعیت، پژوهشکده حکمرانی جمعیت و خانواده، دانشگاه جامع امام حسین(ع)، تهران، ایران | ||
| 2استادیار، گروه جامعهشناسی، دانشکده علوم انسانی، دانشگاه اراک، اراک، ایران | ||
| 3دانشجوی دکتری نانوبیوتکنولوژی، دانشگاه جامع امام حسین (ع)، تهران، ایران | ||
| تاریخ دریافت: 14 تیر 1404، تاریخ بازنگری: 11 مرداد 1404، تاریخ پذیرش: 01 مهر 1404 | ||
| چکیده | ||
| در پژوهش حاضر، تحقیقات جهانی درباره تأثیر نانوذرات هوا بر ناباروری در دو دهه اخیر (2000-2024) با استفاده از رویکرد علمسنجی و نقشهبرداری موضوعی تحلیل شد. مطالعات نشان میدهند که از دهه 2000، تمرکز اولیه بر مکانیسمهای سمیت حاد نانوذرات، مانند استرس اکسیداتیو و آسیب به DNA، بوده است. با پیشرفت فناوری و افزایش نگرانیهای زیستمحیطی، در دهه دوم (2010-2020)، توجه به اثرات مزمن و بیننسلی، بهویژه بر کیفیت اسپرم و سلامت جنین، افزایش یافت. نقشهبرداری موضوعی سه خوشه اصلی را شناسایی کرد: خوشه مکانیسمهای سمی (استرس اکسیداتیو و آپوپتوز)، خوشه مطالعات حیوانی (تأثیر بر اسپرم و بیضه)، و خوشه پژوهشهای انسانی (اختلالات هورمونی و ناباروری). تحلیل علمسنجی حاکی از رشد انتشارات، بهویژه در اروپا و آسیا است. با این حال، شکافهایی در بررسی اثرات بر زنان، پیامدهای بلندمدت، و راهکارهای محافظتی (مانند آنتیاکسیدانها) مشاهده شد. این تحلیل بر ضرورت توسعه چارچوبهای نظری جامع، استانداردسازی پروتکلهای ارزیابی سمیت، و سیاستگذاری برای کاهش مواجهه با نانوذرات تأکید دارد.. | ||
| کلیدواژهها | ||
| نانوذرات هوا؛ آلودگی هوا؛ ناباروری؛ علم سنجی؛ نقشه برداری موضوعی | ||
| عنوان مقاله [English] | ||
| Analysis of Global Research Trends on Airborne Nanoparticles and Infertility in the Last Two Decades: A Scientometric and Topic Mapping Approach | ||
| نویسندگان [English] | ||
| Mohammad Arefkhani1؛ Zahra Ghorbani2؛ Amir Rezaei3 | ||
| 1PhD student , Population Health Department, Population Center, Imam Hossein University, Tehran, Iran | ||
| 2Assistant Professor, Faculty member, Department of Sociology, Faculty of Humanities, University of Arak, Arak, Iran. | ||
| 3PhD student in Nanobiotechnology, Imam Hossein University, Tehran, Iran | ||
| چکیده [English] | ||
| In the present study, global research on the impact of airborne nanoparticles on infertility over the past two decades (2000–2024) was analyzed using a scientometric and thematic mapping approach. Findings indicate that since the early 2000s, initial research has primarily focused on the mechanisms of acute nanoparticle toxicity, such as oxidative stress and DNA damage. With the advancement of technology and growing environmental concerns, the second decade (2010–2020) witnessed a shift toward investigating chronic and transgenerational effects, particularly on sperm quality and fetal health. Thematic mapping identified three main clusters: the toxicological mechanisms cluster (oxidative stress and apoptosis), the animal studies cluster (effects on sperm and testicular function), and the human research cluster (hormonal disruptions and infertility). Scientometric analysis revealed a growth in publications, especially in Europe and Asia. However, noticeable gaps were observed regarding the effects on women, long-term consequences, and protective strategies (such as antioxidants). This analysis highlights the need to develop comprehensive theoretical frameworks, standardize toxicity assessment protocols, and implement policies aimed at reducing exposure to nanoparticles. | ||
| کلیدواژهها [English] | ||
| Airborne nanoparticles, Air pollution, Infertility, Scientometrics, Thematic mapping | ||
| مراجع | ||
|
Ahmad, K. E., Abd El-Aziz, R. M., & Abd El-Emam, M. M. (2017). Ameliorative Effects of Curcumin-Zinc Oxide Nanoparticles Conjugate on Cyclophosphamide-Induced Infertility in Male Rats. Zagazig Veterinary Journal, 45(Supplementary 1), 126-132. https://doi.org/10.21608/zvjz.2019.28657 Al-Musawi, M. M. S., Al-Shmgani, H., & Al-Bairuty, G. A. (2022). Histopathological and Biochemical Comparative Study of Copper Oxide Nanoparticles and Copper Sulphate Toxicity in Male Albino Mice Reproductive System. International journal of biomaterials, 2022, 4877637. https://doi.org/10.1155/2022/4877637 Aloisi, M., Rossi, G., Colafarina, S., Guido, M., Cecconi, S., & Poma, A. M. G. (2022). The Impact of Metal Nanoparticles on Female Reproductive System: Risks and Opportunities. International Journal of Environmental Research and Public Health, 19(21), 13748. https://doi.org/10.3390/ijerph192113748 Ankita Meher, Ashish Tandi, Srikanta Moharana, Subhendu Chakroborty, Susnata Sovalin Mohapatra, Arijit Mondal, Suddhasattya Dey, Prakash Chandra, (2024). Silver nanoparticle for biomedical applications: A review, Hybrid Advances, Volume 6, 100184, ISSN 2773-207X, https://doi.org/10.1016/j.hybadv.2024.100184 Arato I, Giovagnoli S, Di Michele A, Bellucci C, Lilli C, Aglietti MC, Bartolini D, Gambelunghe A, Muzi G, Calvitti M, Eugeni E, Gaggia F, Baroni T, Mancuso F and Luca G (2023) Nickel oxide nanoparticles exposure as a risk factor for male infertility: “In vitro” effects on porcine pre-pubertal Sertoli cells. Front. Endocrinol. 14:1063916. https://doi.org/10.3389/fendo.2023.1063916 Samrot, A. V., & Noel Richard Prakash, L. X. (2023). Nanoparticles Induced Oxidative Damage in Reproductive System and Role of Antioxidants on the Induced Toxicity. Life, 13(3), 767. https://doi.org/10.3390/life13030767 Brito, J. L. M., Lima, V. N., Jivago, J. L. P. R., Marangon, A. R. M., Vinícius-Araújo, M., Bakuzis, A. F., Santos, J. d. A. R. d., Souza, P. E. N., Azevedo, R. B., & Lucci, C. M. (2025). Achieving Permanent Male Infertility by Magnetic Nanoparticle Hyperthermia: A Breakthrough in Animal Fertility Management. Pharmaceutics, 17(5), 602. https://doi.org/10.3390/pharmaceutics17050602 Carré, Julie & Gatimel, Nicolas & Moreau, Jessika & Parinaud, Jean & Roger, Leandri. (2017). Does air pollution play a role in infertility?: A systematic review. Environmental Health. https://doi.org/10.1186/s12940-017-0291-8 Checa Vizcaíno, M. A., González-Comadran, M., & Jacquemin, B. (2016). Outdoor air pollution and human infertility: a systematic review. Fertility and sterility, 106(4), 897–904.e1. https://doi.org/10.1016/j.fertnstert.2016.07.1110 Eberhard, T., Casillas, G., Zarus, G.M. et al. (2024). Systematic review of microplastics and nanoplastics in indoor and outdoor air: identifying a framework and data needs for quantifying human inhalation exposures. J Expo Sci Environ Epidemiol 34, 185–196. https://doi.org/10.1038/s41370-023-00634-x Eleyan, M., Ibrahim, K. A., Mohamed, R. A., Hussien, M., Zughbur, M. R., Aldalou, A. R., Masad, A., El-Rahman, H. A. A., & Abdelgaid, H. A. (2024). Quercetin diminishes the apoptotic pathway of magnetite nanoparticles in rats' ovary: Antioxidant status and hormonal profiles. Environmental analysis, health and toxicology, 39(3), e2024025. https://doi.org/10.5620/eaht.2024025 Fadl, Marwa & Abdellateif, Abd-El-karim & Khandel, Ahmed & Aboella, Adel. (2023). Assessment of Reproductive Toxicity of Silver Nanoparticles on Male Albino Mice "Mus musculus". Egyptian Academic Journal of Biological Sciences, B. Zoology. https://doi.org/10.21608/eajbsz.2023.288521 Haghighi Boroujeni, P., & Tavallaei, R. (2022). Interpretive structural modeling of "organizational knowledge map development". Strategic Management of Organizational Knowledge, 5(4), 45-11. https://doi.org/10.47176/smok.2022.1514 Habas, K., Demir, E., Guo, C., Brinkworth, M. H., & Anderson, D. (2021). Toxicity mechanisms of nanoparticles in the male reproductive system. Drug Metabolism Reviews, 53(4), 604–617. https://doi.org/10.1080/03602532.2021.1917597 Hunt K, Davies A, Fraser A, Burden C, Howell A, Buckley K, et al. (2024). Exposure to microplastics and human reproductive outcomes: A systematic review. BJOG. 131(5): 675–683. https://doi.org/10.1111/1471-0528.17756 Iftikhar, M., Noureen, A., Uzair, M., Jabeen, F., Abdel Daim, M., & Cappello, T. (2021). Perspectives of Nanoparticles in Male Infertility: Evidence for Induced Abnormalities in Sperm Production. International journal of environmental research and public health, 18(4), 1758. https://doi.org/10.3390/ijerph18041758 Siddiqi, N., Fatima, S., Sharma, B., & Samir Elrobh, M. (2022). In-Utero Neurotoxicity of Nanoparticles. IntechOpen. https://doi.org/10.5772/intechopen.101452 José Portugal, Carmen Bedia, Fulvio Amato, Ana T. Juárez-Facio, Rodopi Stamatiou, Antigone Lazou, Chiara E. Campiglio, Karine Elihn, Benjamin Piña, (2024). Toxicity of airborne nanoparticles: Facts and challenges, Environment International, Volume 190, 108889, ISSN 0160-4120, https://doi.org/10.1016/j.envint.2024.108889 Klein, J.-P., Mery, L., Boudard, D., Ravel, C., Cottier, M., & Bitounis, D. (2023). Impact of Nanoparticles on Male Fertility: What Do We Really Know? A Systematic Review. International Journal of Molecular Sciences, 24(1), 576. https://doi.org/10.3390/ijms24010576 Mahsa Nazari, Ronak Shabani, Marziyeh Ajdary, Mohsen Ashjari, Reza Shirazi, Azam Govahi, Fatemeh Kermanian, Mehdi Mehdizadeh, (2023). Effects of Au@Ag core-shell nanostructure with alginate coating on male reproductive system in mice, Toxicology Reports, Volume 10,Pages 104-116. https://doi.org/10.1016/j.toxrep.2023.01.003 Minghui F, Ran S, Yuxue J and Minjia S (2023) Toxic effects of titanium dioxide nanoparticles on reproduction in mammals. Front. Bioeng. Biotechnol. 11:1183592. https://doi.org/10.3389/fbioe.2023.1183592 Mirgalooye Bayat Sh, Farzaneh F, Mirgalobayat Sh. (2024). Comparative Analysis of the Effects of Magnesium Oxide Nanoparticles on Sperm Parameters in Fresh and Frozen Samples. J Reprod Infertil.25(2):148-156. Moretti, E., Terzuoli, G., Renieri, T., Iacoponi, F., Castellini, C., Giordano, C. and Collodel, G. (2013), In vitro effect of gold and silver nanoparticles on human spermatozoa. Andrologia, 45: 392-396. https://doi.org/10.1111/and.12028 Moridi H, Hosseini S A, Shateri H, Kheiripour N, Kaki A, Hatami M et al . (2018). Protective effect of cerium oxide nanoparticle on sperm quality and oxidative damage in malathion-induced testicular toxicity in rats: An experimental study. IJRM 16 (4) :261-266 Said, A. A., Nasr, Y., Galal, A. A. A., Abdelhamid, A. E., Mohamed, H. A., Metwally, M. M. M., Said, M. A., Nassan, M. A., Dahran, N., & Mohamed, A. A.-R. (2022). Concerns with Male Infertility Induced by Exposure to Titanium Nanoparticles and the Supporting Impact of Pelargonium graveolens Essential Oil: Morphometric Records in Male-Wistar Rats. Life, 12(5), 639. https://doi.org/10.3390/life12050639 Saman Sargazi, Zahra Ahmadi, Mahmood Barani, Abbas Rahdar, Soheil Amani, Martin F. Desimone, Sadanand Pandey, George Z. Kyzas, (2022). Can nanomaterials support the diagnosis and treatment of human infertility? A preliminary review, Life Sciences, Volume 299,120539. https://doi.org/10.1016/j.lfs.2022.120539 Samrot, A. V., & Noel Richard Prakash, L. X. (2023). Nanoparticles Induced Oxidative Damage in Reproductive System and Role of Antioxidants on the Induced Toxicity. Life, 13(3), 767. https://doi.org/10.3390/life13030767 Santonastaso, Marianna & Mottola, Filomena & Iovine, Concetta & Colacurci, N & Rocco, Lucia. (2021). P–033 In vitro protective effect of α -tocopherol and anthocyanin against TiO2-NPs induced genotoxicity on human spermatozoa. Human Reproduction. 36. https://doi.org/10.1093/humrep/deab130.032 Shandilya, R., Pathak, N., Lohiya, N. K., Sharma, R. S., & Mishra, P. K. (2020). Nanotechnology in reproductive medicine: Opportunities for clinical translation. Clinical and experimental reproductive medicine, 47(4), 245–262. https://doi.org/10.5653/cerm.2020.03650 Shaoyong, W., Wang, W., Pan, B., Liu, R., Yin, L., Wangjie, R., Tian, H., Wang, Y., & Jin, M. (2024). Transgenerational Inheritance Effects of Copper Oxide Nanoparticles (CuONPs) Induced Asthenospermia and Infertility via Gamete H3K9me3 Insufficiency Pathway in Mice. ACS nano, 10.1021/acsnano.4c05660. Advance online publication. https://doi.org/10.1021/acsnano.4c05660 Shaoyong, Weike and Xu, Bocheng and Liu, Yalin and Pan, Bo and Wang, Yizhen and Jin, Mingliang, Exposure to Copper Oxide Nanoparticles Causes Human Infertility Risk and Damages the Quality of the Human Sperm Via the 5'Amp-Activated Protein Kinase-Mediated Signaling Pathway in Vitro. Available at SSRN: https://ssrn.com/abstract=4052477 or http://dx.doi.org/10.2139/ssrn.4052477 Smith, M. A., Michael, R., Aravindan, R. G., Dash, S., Shah, S. I., Galileo, D. S., & Martin-DeLeon, P. A. (2015). Anatase titanium dioxide nanoparticles in mice: evidence for induced structural and functional sperm defects after short-, but not long-, term exposure. Asian journal of andrology, 17(2), 261–268. https://doi.org/10.4103/1008-682X.143247 Wei, Y. S., Chen, Y. L., Li, W. Y., Yang, Y. Y., Lin, S. J., Wu, C. H., Yang, J. I., Wang, T. E., Yu, J., & Tsai, P. S. (2023). Antioxidant Nanoparticles Restore Cisplatin-Induced Male Fertility Defects by Promoting MDC1-53bp1-Associated Non-Homologous DNA Repair Mechanism and Sperm Intracellular Calcium Influx. International journal of nanomedicine, 18, 4313–4327. https://doi.org/10.2147/IJN.S408623 Zheng, H., Liang, G., Guan, C., Liu, L., Dong, J., Zhao, J., Tang, M., & Kong, L. (2024). Mitochondrial Fission in Nickel Nanoparticle-Induced Reproductive Toxicity: An In Vitro GC-1 Cell Study. Nanomaterials, 14(8), 689. https://doi.org/10.3390/nano14080689 | ||
|
آمار تعداد مشاهده مقاله: 203 تعداد دریافت فایل اصل مقاله: 44 |
||